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Seong-Yun Jeong Selected Research

(5- (4- amino- 6- bromo- 5- carbamoyl- 1H- pyrrolo(2,3- d)pyrimidin- 1- yl)- 3,4- dihydroxytetrahydrofuran- 2- yl)methyl isobutyrate

1/2017Ibulocydine sensitizes human hepatocellular carcinoma cells to TRAIL-induced apoptosis via calpain-mediated Bax cleavage.
8/2014Ibulocydine sensitizes human cancers to radiotherapy by induction of mitochondria-mediated apoptosis.

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Seong-Yun Jeong Research Topics

Disease

51Neoplasms (Cancer)
01/2022 - 04/2006
9Lung Neoplasms (Lung Cancer)
01/2019 - 01/2011
7Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2018 - 05/2010
6Hepatocellular Carcinoma (Hepatoma)
01/2018 - 04/2008
5Breast Neoplasms (Breast Cancer)
12/2017 - 11/2012
4Stomach Neoplasms (Stomach Cancer)
12/2021 - 10/2017
4Infections
01/2015 - 07/2010
3Colorectal Neoplasms (Colorectal Cancer)
10/2020 - 02/2009
3Colonic Neoplasms (Colon Cancer)
09/2019 - 12/2013
3Prostatic Neoplasms (Prostate Cancer)
01/2018 - 04/2012
3Pancreatic Neoplasms (Pancreatic Cancer)
06/2017 - 02/2016
3Neoplasm Metastasis (Metastasis)
01/2017 - 05/2010
3Necrosis
01/2013 - 11/2009
2Lymphatic Metastasis
01/2017 - 02/2016
2Adenocarcinoma of Lung
04/2016 - 02/2015
2Leukemia
01/2015 - 01/2010
2Hyperthermia
01/2011 - 05/2009
1Ovarian Neoplasms (Ovarian Cancer)
01/2022
1Aggressive Fibromatosis (Desmoid)
05/2021
1Sarcoma (Soft Tissue Sarcoma)
07/2019
1Cardiotoxicity
01/2018
1Adenoid Cystic Carcinoma (Cylindroma)
12/2017
1Edema (Dropsy)
12/2017
1Alopecia (Baldness)
12/2017
1Cholangiocarcinoma
06/2017
1Melanoma (Melanoma, Malignant)
01/2017
1Weight Loss (Weight Reduction)
12/2015
1Body Weight (Weight, Body)
03/2015

Drug/Important Bio-Agent (IBA)

7Proteins (Proteins, Gene)FDA Link
10/2020 - 02/2009
5Peptides (Polypeptides)IBA
10/2020 - 11/2009
4Docetaxel (Taxotere)FDA Link
01/2022 - 11/2016
4Therapeutic UsesIBA
01/2022 - 06/2012
4Pharmaceutical PreparationsIBA
06/2017 - 06/2012
4LigandsIBA
01/2017 - 01/2013
3ErbB Receptors (EGF Receptor)IBA
01/2019 - 09/2013
3Doxorubicin (Adriamycin)FDA LinkGeneric
01/2018 - 01/2011
3CaspasesIBA
12/2013 - 11/2012
2Trastuzumab (Herceptin)FDA Link
12/2021 - 01/2018
2Fluorouracil (Carac)FDA LinkGeneric
10/2020 - 06/2017
2Biomarkers (Surrogate Marker)IBA
07/2019 - 06/2017
2Histone Deacetylase InhibitorsIBA
01/2018 - 04/2012
2Antineoplastic Agents (Antineoplastics)IBA
12/2017 - 11/2009
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2017 - 10/2016
2(5- (4- amino- 6- bromo- 5- carbamoyl- 1H- pyrrolo(2,3- d)pyrimidin- 1- yl)- 3,4- dihydroxytetrahydrofuran- 2- yl)methyl isobutyrateIBA
01/2017 - 08/2014
2SurvivinIBA
10/2016 - 01/2013
2Estrogen ReceptorsIBA
01/2015 - 12/2013
2Biological ProductsIBA
06/2012 - 01/2010
21-methylxanthineIBA
05/2009 - 02/2009
2Caffeine (No Doz)FDA LinkGeneric
05/2009 - 02/2009
1Immunoconjugates (Immunoconjugate)IBA
12/2021
1human ERBB2 proteinIBA
12/2021
1Low Density Lipoprotein Receptor-Related Protein-1 (LDL-Receptor Related Protein)IBA
10/2020
1Human Serum AlbuminFDA LinkGeneric
10/2020
1pifithrinIBA
09/2019
1Small Interfering RNA (siRNA)IBA
09/2019
1C-Reactive ProteinIBA
07/2019
1CrizotinibIBA
01/2019
1VorinostatFDA Link
01/2019
1Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2019
1Sulfhydryl Compounds (Thiols)IBA
01/2019
1olaparibIBA
01/2019
1Cycloheximide (Cicloheximide)IBA
01/2019
1Phosphotransferases (Kinase)IBA
01/2019
1gambogic acidIBA
01/2019
1Oxygen (Dioxygen)IBA
01/2019
1pyrrolidine dithiocarbamic acidIBA
01/2018
1Androgen Receptors (Androgen Receptor)IBA
01/2018
1prolinedithiocarbamate (PDTC)IBA
01/2018
1chrysinIBA
12/2017
1Cisplatin (Platino)FDA LinkGeneric
10/2017
1Peptide LibraryIBA
10/2017
1NanocapsulesIBA
10/2017
1Type 4 Fibroblast Growth Factor ReceptorIBA
06/2017
1Formaldehyde (Formol)FDA Link
06/2017
1Bile Acids and Salts (Bile Acids)IBA
06/2017
1ParaffinIBA
06/2017
1CalpainIBA
01/2017
1Beclin-1IBA
06/2016
1tyrosine receptor (receptor, tyrosine)IBA
02/2016
1Protein Kinases (Protein Kinase)IBA
02/2016
1poly(lactide) (polylactic acid)IBA
07/2015
1GoldIBA
06/2015
1CreatinineIBA
03/2015
1Urea (Carbamide)FDA LinkGeneric
03/2015
1NitrogenIBA
03/2015
1LipidsIBA
01/2015
1Cytotoxins (Cytolysins)IBA
01/2015

Therapy/Procedure

21Radiotherapy
05/2021 - 05/2010
14Therapeutics
12/2021 - 04/2008
3Drug Therapy (Chemotherapy)
01/2018 - 12/2015
2Adjuvant Radiotherapy
10/2020 - 07/2019
1Aftercare (After-Treatment)
11/2020
1Precision Medicine
10/2020
1Neoadjuvant Therapy
10/2020
1Immunotherapy
03/2020
1Intraperitoneal Injections
09/2019
1Castration
01/2018
1Operative Surgical Procedures
02/2016
1Intensity-Modulated Radiotherapy (Radiotherapy, Intensity Modulated)
12/2015
1Salvage Therapy
11/2015